This book covers our current understanding of the role of mesenchymal stem cells mscs and other mesenchymal progenitors in skeletal regeneration encompassing bone cartilage and whole joint regeneration the expansion reflects developments in the field to include data on the use of mscs in drug development growth factors scaffolds and biomechanical manipulations for skeletal trauma and diseases including osteoporosis and arthritis. Purchase mesenchymal stem cells and skeletal regeneration 1st edition print book e book isbn 9780124079151 9780124081314. Skeletal muscle injuries have bothered doctors and caused great burdens to the public medical insurance system for a long time once injured skeletal muscles usually go through the processes of inflammation repairing and remodeling if repairing and remodeling stages are out of balance scars will . Mesenchymal stem cell msc transplantation is used for treatment of many diseases the paracrine role of mscs in tissue regeneration is attracting particular attention we investigate the role of msc exosomes in skeletal muscle regeneration msc exosomes promote myogenesis and angiogenesis in vitro and muscle regeneration in an in vivo model of muscle injury although msc exosomes had low concentrations of muscle repair related cytokines a number of repair related mirnas were identified
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